P140CAP CONTROLS FEMALE FERTILITY IN MICE ACTING VIA GLUTAMATERGIC AFFERENCE ON HYPOTHALAMIC GONADOTROPIN-RELEASING HORMONE NEURONS

p140Cap Controls Female Fertility in Mice Acting via Glutamatergic Afference on Hypothalamic Gonadotropin-Releasing Hormone Neurons

p140Cap, encoded by the gene SRCIN1 (SRC kinase signaling inhibitor 1), is an adaptor/scaffold protein highly expressed in the mouse brain, participating in several pre- and post-synaptic mechanisms.p140Cap knock-out (KO) female mice show severe hypofertility, delayed puberty onset, altered estrus cycle, reduced ovulation, and defective production

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Suturing the Anterior Cruciate Ligament Using a No. 16 Intravenous Catheter Needle in Avulsion Anterior Cruciate Ligament Injury

Avulsion anterior cruciate ligament injuries are more common in pediatric patients.There are several methods of fixation available for these injuries (tibial intercondylar eminence fractures), such as the pullout suture technique, screw fixation, and suture anchor fixation.Currently, a pullout technique is widely used for fixation.We purpose a Chai

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The Effects of Social Mobility

The question of how social mobility affects outcomes, Paper such as political preferences, wellbeing, and fertility, has long been of interest to sociologists.But finding answers to this question has been plagued by, on the one hand, the non-identifiability of "mobility effects" as they are usually conceived in this literature, and, on the other, t

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An adaptive instinctive reaction strategy based on Harris hawks optimization algorithm for numerical optimization problems

An adaptive Harris hawks optimization (HHO) algorithm is proposed to solve the non-linearly constrained optimization problems.The algorithm, namely, instinctive reaction strategy based on HHO (IRSHHO), combines the instinctive reaction strategy (IRS) with the HHO algorithm.In IRSHHO, Paper the increment of step length decreases with the increase in

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